Structure of PDB 5ik5 Chain A Binding Site BS04

Receptor Information
>5ik5 Chain A (length=379) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTMVHGPCVAESEPALLTGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEV
RTEAESGLLFYMARINHADFATVQLRNGFPYFSYDLGSGDTSTMIPTKIN
DGQWHKIKIVRVKQEGILYVDDASSQTISPKKADILDVVGILYVGGLPIN
YTTRRIGPVTYSLDGCVRNLHMEQAPVDLDQPTSSFHVGTCFANAESGTY
FDGTGFAKAVGGFKVGLDLLVEFEFRTTRPTGVLLGVSSQKMDGMGIEMI
DEKLMFHVDNGAGRFTAIYDAEIPGHMCNGQWHKVTAKKIKNRLELVVDG
NQVDAQSPNSASTSADTNDPVFVGGFPGGLNQFGLTTNIRFRGCIRSLKL
TKGTGKPLEVNFAKALELRGVQPVSCPTT
Ligand information
Ligand ID4MU
InChIInChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3
InChIKeyHSHNITRMYYLLCV-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C2Oc1cc(O)ccc1C(=C2)C
OpenEye OEToolkits 1.5.0CC1=CC(=O)Oc2c1ccc(c2)O
CACTVS 3.341CC1=CC(=O)Oc2cc(O)ccc12
FormulaC10 H8 O3
Name7-hydroxy-4-methyl-2H-chromen-2-one;
4-methylumbelliferone
ChEMBLCHEMBL12208
DrugBankDB07118
ZINCZINC000000058121
PDB chain5ik5 Chain A Residue 4013 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ik5 Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Resolution1.39 Å
Binding residue
(original residue number in PDB)		G2826 K2870
Binding residue
(residue number reindexed from 1)		G87 K131
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5ik5, PDBe:5ik5, PDBj:5ik5
PDBsum5ik5
PubMed27526028
UniProtQ60675|LAMA2_MOUSE Laminin subunit alpha-2 (Gene Name=Lama2)

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