Structure of PDB 5d91 Chain A Binding Site BS04

Receptor Information

>5d91 Chain A (length=335) Species: 224325,288705

MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDY
LIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIE
KYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLIGSRGLFAAIFLPIAR
LLADWGVSPDAVTVVGTLGVMAGALIFYPMGQLFWGTVVITVFVFSDIID
GLMARLLFREGPWGAFLDSYLDRVGDSSVFTGIVIWFFLGGANPTIAILA
LICLVLSSLVSYSKARAEGLGLTANVGIAERSERLVVVLVATGLVGLGIP
SWVLLVVLIVLAIASVVTIFQRVLTVREQAKAWTA

Ligand information

• Ligand ID: 8K6
• InChI: InChI=1S/C18H38/c1-3-5-7-9-11-13-15-17-18-16-14-12-10-8-6-4-2/h3-18H2,1-2H3
• InChIKey: RZJRJXONCZWCBN-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.385
  OpenEye OEToolkits 1.9.2: CCCCCCCCCCCCCCCCCC
  ACDLabs 12.01: C(CCCCCCCCCCCCCCCC)C
• Formula: C18 H38
• Name: Octadecane;
  N-Octadecane
• ZINC: ZINC000059592152
• PDB chain: 5d91 Chain A Residue 314

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5d91 Structural basis for phosphatidylinositol-phosphate biosynthesis.
• Resolution: 2.501 Å
• Binding residue (original residue number in PDB): S27 A30
• Binding residue (residue number reindexed from 1): S158 A161
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number:
  2.7.8.-

Gene Ontology

Molecular Function

• GO:0016780 phosphotransferase activity, for other substituted phosphate groups

Biological Process

• GO:0008654 phospholipid biosynthetic process

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:5d91, PDBe:5d91, PDBj:5d91
• PDBsum: 5d91
• PubMed: 26510127
• UniProt: A9WSF5;
  O27985