Structure of PDB 5d43 Chain A Binding Site BS04

Receptor Information
>5d43 Chain A (length=150) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMIS
EVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK
NLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLYHH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5d43 Chain A Residue 1204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5d43 Crystal Structure of Wild-Type Centrin 1 from Mus musculus Occupied by Ca2.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		D150 D152 D154 E156 E161
Binding residue
(residue number reindexed from 1)		D126 D128 D130 E132 E137
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0008017 microtubule binding
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0032795 heterotrimeric G-protein binding
GO:0046872 metal ion binding
Biological Process
GO:0034605 cellular response to heat
GO:0051301 cell division
Cellular Component
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005929 cilium
GO:0032391 photoreceptor connecting cilium
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5d43, PDBe:5d43, PDBj:5d43
PDBsum5d43
PubMed29037133
UniProtP41209|CETN1_MOUSE Centrin-1 (Gene Name=Cetn1)

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