Structure of PDB 5cyx Chain A Binding Site BS04

Receptor Information

>5cyx Chain A (length=318) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NSPPSFGVNMTLVTLPEDLPVGAVAFWLVATLTYGISGPNASYFSVNANT
GEVKLASPLDFETVPFFKITISTSDGLNIRTAEMQVIVEDRNDNIPVFLN
TEFSTSINETLPVGSVVFSVLAEDKDTGTAGLVQYFIEKVIPSTANSNNL
FRILENGSIVLNDTLSYNNKSAFYQLELKACDSGGILDNKPKTQCSQPVF
VSISVIDEPDLDPRFIREFYSASVAEDATLGTSVLTVEAVDSDKGINDIV
TYSVSNSTRPGWFDIREDGVIFVNGSLDREQLLLENEEVQIQVTATEKNL
NIYGQEAKASMWVTIRVT

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

5cyx Chain A Residue 1004 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5cyx Crystal Structure of Mouse Protocadherin-24 EC1-3
Resolution	2.1 Å
Binding residue (original residue number in PDB)	E115 D213 E214 D216 D249
Binding residue (residue number reindexed from 1)	E109 D207 E208 D210 D243
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609	cell-cell adhesion

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:5cyx, PDBe:5cyx, PDBj:5cyx
PDBsum	5cyx
PubMed
UniProt	E9Q7P9\|CDHR2_MOUSE Cadherin-related family member 2 (Gene Name=Cdhr2)

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