Structure of PDB 5co8 Chain A Binding Site BS04

Receptor Information

>5co8 Chain A (length=393) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARG
GSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKPNGVSTAMAKRLIRLFGF
TAHDAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGP
PTHVTLHDAKKIAEGPSGLDREGMVLVALMSGGDGIPGCGIKVACQAAKA
GFGKELCAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEVLRYY
THPVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAIKLIK
VLAPGLLVQRCLDRYEESTLVKGISMRREHFSTDATPELRVSFIPAELVG
LDPGQEPEVPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

5co8 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5co8 Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	E122 D141 D143
Binding residue (residue number reindexed from 1)	E110 D129 D131
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004518	nuclease activity
GO:0008821	crossover junction DNA endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:5co8, PDBe:5co8, PDBj:5co8
PDBsum	5co8
PubMed	26686639
UniProt	G0RYN2

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