Structure of PDB 5a2h Chain A Binding Site BS04

Receptor Information

>5a2h Chain A (length=147) Species: 3702 (Arabidopsis thaliana)

DQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDM
INEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFIS
AAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMAK

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 5a2h Chain A Residue 1153

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5a2h Crystal Structure of Arabidopsis Thaliana Calmodulin7 and Insight Into its Mode of DNA Binding.
• Resolution: 2.27 Å
• Binding residue (original residue number in PDB): D130 D132 D134 Q136 E141
• Binding residue (residue number reindexed from 1): D128 D130 D132 Q134 E139
• Annotation score: 4

Enzymatic activity

• Catalytic site (original residue number in PDB): V36
• Catalytic site (residue number reindexed from 1): V34

Gene Ontology

Molecular Function

• GO:0005509 calcium ion binding
• GO:0005515 protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0005513 detection of calcium ion
• GO:0010099 regulation of photomorphogenesis
• GO:0050832 defense response to fungus

Cellular Component

• GO:0005634 nucleus
• GO:0005829 cytosol
• GO:0005886 plasma membrane

External links

• PDB: RCSB:5a2h, PDBe:5a2h, PDBj:5a2h
• PDBsum: 5a2h
• PubMed: 27500568
• UniProt: P59220|CALM7_ARATH Calmodulin-7 (Gene Name=CAM7)