Structure of PDB 4r2r Chain A Binding Site BS04

Receptor Information
>4r2r Chain A (length=88) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHL
KTHTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4r2r Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4r2r Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.
Resolution2.089 Å
Binding residue
(original residue number in PDB)		C385 C388 H401 H405
Binding residue
(residue number reindexed from 1)		C37 C40 H53 H57
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4r2r, PDBe:4r2r, PDBj:4r2r
PDBsum4r2r
PubMed25258363
UniProtP19544|WT1_HUMAN Wilms tumor protein (Gene Name=WT1)

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