Structure of PDB 4pv2 Chain A Binding Site BS04

Receptor Information
>4pv2 Chain A (length=155) Species: 3885 (Phaseolus vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGWAIAVHGGAGVDPTLPLERQEEAKQLLTRCLNLGISALNSNVPAIDVV
ELVVRELETDPLFNSGRGSALTEKGTVEMEASIMDGPKRRCGAVSGLTTV
KNPISLARLVMDKSPHSYIAFSGAEDFARQQGVEVVDNEYFVTPDNVGML
KLAKE
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain4pv2 Chain A Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4pv2 Na+/K+ exchange switches the catalytic apparatus of potassium-dependent plant L-asparaginase
Resolution1.79 Å
Binding residue
(original residue number in PDB)		C92 V111 M112 S115 P116 H117 S118
Binding residue
(residue number reindexed from 1)		C91 V110 M111 S114 P115 H116 S117
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) S66
Catalytic site (residue number reindexed from 1) S65
Enzyme Commision number 3.5.1.1: asparaginase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:4pv2, PDBe:4pv2, PDBj:4pv2
PDBsum4pv2
PubMed25004963
UniProtV7CU13

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