Structure of PDB 4juo Chain A Binding Site BS04

Receptor Information
>4juo Chain A (length=479) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDS
NTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEP
TVLPAAFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKID
KLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKE
QIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIEL
KKDANTELVLNYLFKYTDLQINYNFNMVAIDNFTPRQVIVPILSSYIAHR
REVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKE
NLKVSYDFTEEQAEAIVTLQLYRLTNDVVVLQEEEAELREKIAMLAAIIG
DERTMYNLMKKELREVKKKFTPRLSSLED
Ligand information
Receptor-Ligand Complex Structure
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PDB4juo Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport.
Resolution6.53 Å
Binding residue
(original residue number in PDB)		R117 Y118 I170 N326
Binding residue
(residue number reindexed from 1)		R115 Y116 I168 N324
Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006265 DNA topological change
Cellular Component
GO:0005694 chromosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4juo, PDBe:4juo, PDBj:4juo
PDBsum4juo
PubMed23965305
UniProtP72525|PARC_STRPN DNA topoisomerase 4 subunit A (Gene Name=parC)

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