Structure of PDB 4gv9 Chain A Binding Site BS04

Receptor Information

>4gv9 Chain A (length=198) Species: 11622 (Lassa virus Josiah) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

FGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIH
FFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQ
GSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGV
VVEKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRPRVVL

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

4gv9 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4gv9 Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
Resolution	2.46 Å
Binding residue (original residue number in PDB)	E399 C506 H509 C529
Binding residue (residue number reindexed from 1)	E37 C144 H147 C161
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.1.13.-

External links

PDB	RCSB:4gv9, PDBe:4gv9, PDBj:4gv9
PDBsum	4gv9
PubMed	23615902
UniProt	P13699\|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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