Structure of PDB 4cuo Chain A Binding Site BS04

Receptor Information

>4cuo Chain A (length=306) Species: 309271 (Ficus benghalensis)

QLTPTFYRSTCPNVTSIVRGVIQDALQTDLRIPASLIRLHFHDCFVNGCD
GSLLLDNSDTIESEKQAAPNNNSARGFDVVDNIKTAVENACPGVVSCADI
LTIAAEQSVWLSGGPSWPVPLGRRDSLTANRTLANQTLPSPFLTLDQLKT
DFSDQGLNTTDLVALSGAHTFGRAQCQFFSQRLYNFSATGSPDPTLNTTL
LETLRNICPQGGNGSTITNLDQTTPDAFDNKYFSNLQTQYGILQTDQELF
STKGANTTAIVTKFSANQSAFFNSFVASMIKMGNIGVLTNDEGEIRSNCR
SVNGGA

Ligand information

• Ligand ID: CO3
• InChI: InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
• InChIKey: BVKZGUZCCUSVTD-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: C(=O)([O-])[O-]
  ACDLabs 10.04
  CACTVS 3.341: [O-]C([O-])=O
• Formula: C O3
• Name: CARBONATE ION
• DrugBank: DB14531
• PDB chain: 4cuo Chain A Residue 1335

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4cuo Post-Translational Modification and Extended Glycosylation Pattern of a Plant Latex Peroxidase of Native Source Characterized by X-Ray Crystallography.
• Resolution: 1.67 Å
• Binding residue (original residue number in PDB): T15 R19 Q107
• Binding residue (residue number reindexed from 1): T15 R19 Q107
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): R38 H42 N70 H169
• Catalytic site (residue number reindexed from 1): R38 H42 N70 H169
• Enzyme Commision number: 1.11.1.7: peroxidase.

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0140825 lactoperoxidase activity

Biological Process

• GO:0006979 response to oxidative stress
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:4cuo, PDBe:4cuo, PDBj:4cuo
• PDBsum: 4cuo
• PubMed: 24980207
• UniProt: A0A087WNH2