Structure of PDB 3v5u Chain A Binding Site BS04

Receptor Information
>3v5u Chain A (length=297) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGT
SLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKN
LQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAKN
NPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLVAF
GTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLPAE
NVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRMGGG
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain3v5u Chain A Residue 704 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3v5u Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		E54 N81 E213 D240
Binding residue
(residue number reindexed from 1)		E54 N81 E206 D233
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005262 calcium channel activity
GO:0008273 calcium, potassium:sodium antiporter activity
Biological Process
GO:0006874 intracellular calcium ion homeostasis
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3v5u, PDBe:3v5u, PDBj:3v5u
PDBsum3v5u
PubMed22323814
UniProtQ57556|Y091_METJA Uncharacterized membrane protein MJ0091 (Gene Name=MJ0091)

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