Structure of PDB 3txe Chain A Binding Site BS04

Receptor Information

>3txe Chain A (length=129) Species: 9031 (Gallus gallus)

KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL

Ligand information

• Ligand ID: MEB
• InChI: InChI=1S/C4H8/c1-4(2)3/h1H2,2-3H3
• InChIKey: VQTUBCCKSQIDNK-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 1.7.2: CC(=C)C
  CACTVS 3.370: CC(C)=C
  ACDLabs 12.01: C=C(\C)C
• Formula: C4 H8
• Name: 2-methylprop-1-ene
• ZINC: ZINC000059940055
• PDB chain: 3txe Chain A Residue 135

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3txe Experience with exchange and archiving of raw data: comparison of data from two diffractometers and four software packages on a series of lysozyme crystals.
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): I58 N59 W63 A107 W108
• Binding residue (residue number reindexed from 1): I58 N59 W63 A107 W108
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): E35 N46 D48 S50 D52 N59
• Catalytic site (residue number reindexed from 1): E35 N46 D48 S50 D52 N59
• Enzyme Commision number: 3.2.1.17: lysozyme.

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0005515 protein binding
• GO:0016231 beta-N-acetylglucosaminidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0042802 identical protein binding

Biological Process

• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0050829 defense response to Gram-negative bacterium
• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum

External links

• PDB: RCSB:3txe, PDBe:3txe, PDBj:3txe
• PDBsum: 3txe
• PubMed: 23396873
• UniProt: P00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)