Structure of PDB 3rb7 Chain A Binding Site BS04

Receptor Information
>3rb7 Chain A (length=248) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRMYFEPGHYTVMENCGEFEVRVVRRGDISTYASVEYETQDGTASAGTDF
VGRKGLLSFPPGVDEQRFRIEVIDDDVFEEDECFYIRLFNPSEGVKLAVP
MIATVMILDDDHAGIFAFTDSVFEITESVGRFELKVMRYSGARGTVIVPY
WTENDTATESKDYEGARGELVFENNESEKFIDLFIYEKDVSFKVHIGEPR
LAPDSTHYPKIKEVEKKPVQDLTELDRILLLSKPRNGELTTAYVRIRE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3rb7 Chain A Residue 4 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3rb7 Structural Basis of the Ca(2+) Inhibitory Mechanism of Drosophila Na(+)/Ca(2+) Exchanger CALX and Its Modification by Alternative Splicing.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		E455 D490 E520
Binding residue
(residue number reindexed from 1)		E14 D49 E79
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007154 cell communication
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:3rb7, PDBe:3rb7, PDBj:3rb7
PDBsum3rb7
PubMed22000518
UniProtQ9VDG5|NACX_DROME Sodium/calcium exchanger Calx (Gene Name=Calx)

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