Structure of PDB 3qlc Chain A Binding Site BS04

Receptor Information
>3qlc Chain A (length=127) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLGSMGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYMSDDIS
RDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRRELSTIMDEN
NQWYCYICHPEPLLDLVTACNSVYENL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3qlc Chain A Residue 663 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3qlc ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Resolution2.5 Å
Binding residue
(original residue number in PDB)		C232 C235 C265 C268
Binding residue
(residue number reindexed from 1)		C72 C75 C105 C108
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
External links
PDB RCSB:3qlc, PDBe:3qlc, PDBj:3qlc
PDBsum3qlc
PubMed21666679
UniProtP46100|ATRX_HUMAN Transcriptional regulator ATRX (Gene Name=ATRX)

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