Structure of PDB 3py7 Chain A Binding Site BS04

Receptor Information
>3py7 Chain A (length=500) Species: 83333,337052 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVA
ATGDGPDIIFWAHDRFGGYAQSGLLAEITPAAAFQDKLYPFTWDAVRYNG
KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNL
QEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKN
KHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSAVNYGVTVLPTFK
GQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGA
VALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAA
SGRQTVDAALAAAQTNAAAMDDLDALLADKPFSGLDCLWCREPLTEVDAF
RCMVKDFHVVIREGCRYGACTICLENCLATERRLWQGVPVTGEEAELLHG
KTLDRLCIRCCYCGGKLTKNEKHRHVLFNEPFCKTRANIIRGRCYDCCRH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3py7 Chain A Residue 524 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3py7 Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.
Resolution2.288 Å
Binding residue
(original residue number in PDB)		C476 C479 C510 C513
Binding residue
(residue number reindexed from 1)		C460 C463 C494 C497
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0015144 carbohydrate transmembrane transporter activity
GO:0046872 metal ion binding
GO:1901982 maltose binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0019049 virus-mediated perturbation of host defense response
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0039502 symbiont-mediated suppression of host type I interferon-mediated signaling pathway
GO:0039648 symbiont-mediated perturbation of host ubiquitin-like protein modification
GO:0042956 maltodextrin transmembrane transport
GO:0052150 symbiont-mediated perturbation of host apoptosis
GO:0052170 symbiont-mediated suppression of host innate immune response
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0030430 host cell cytoplasm
GO:0042025 host cell nucleus
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3py7, PDBe:3py7, PDBj:3py7
PDBsum3py7
PubMed23393263
UniProtP06931;
P0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE)

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