Structure of PDB 3oha Chain A Binding Site BS04

Receptor Information
>3oha Chain A (length=516) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDPHMSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLS
KEDPVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFK
KGEDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALAIFKWAC
DLVERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIG
GNYDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCK
GIRDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLD
CGKFEITSFWTLGGVLGKELIDVLDLPHENSIKHIRETWPDNAGQLKEFL
DAKVKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSSRPVVKSMM
SNKNLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTVSIS
LKTKSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYYPL
TKLSMTITNFDIIDLQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3oha Chain A Residue 518 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3oha Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D30 M31 D155
Binding residue
(residue number reindexed from 1)		D34 M35 D159
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3oha, PDBe:3oha, PDBj:3oha
PDBsum3oha
PubMed21070945
UniProtQ04049|POLH_YEAST DNA polymerase eta (Gene Name=RAD30)

[Back to BioLiP]