Structure of PDB 3dkh Chain A Binding Site BS04

Receptor Information
>3dkh Chain A (length=558) Species: 204285 (Melanocarpus albomyces) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDG
VVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKD
TNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVG
TIQINGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLIN
GTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIA
ADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGS
LNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSF
VKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPV
SDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPA
ASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLF
HCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTNP
YPKIDSGA
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain3dkh Chain A Residue 604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3dkh Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H93 H434 H436
Binding residue
(residue number reindexed from 1)		H92 H433 H435
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H93 H95 H138 H140 H431 H434 H436 H502 C503 H504 I505 H508 L513
Catalytic site (residue number reindexed from 1) H92 H94 H137 H139 H430 H433 H435 H501 C502 H503 I504 H507 L512
Enzyme Commision number 1.10.3.2: laccase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0052716 hydroquinone:oxygen oxidoreductase activity
Biological Process
GO:0030245 cellulose catabolic process
GO:0046274 lignin catabolic process
Cellular Component
GO:0043245 extraorganismal space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3dkh, PDBe:3dkh, PDBj:3dkh
PDBsum3dkh
PubMed19780817
UniProtQ70KY3|LAC1_MELAO Laccase-1 (Gene Name=LAC1)

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