Structure of PDB 3axe Chain A Binding Site BS04

Receptor Information
>3axe Chain A (length=234) Species: 59374 (Fibrobacter succinogenes subsp. succinogenes S85) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKDFSGAELYTLEEYQYGKFEARMKMAAASGTVSSMFLYQNGSEIADGRP
WVEVDIEVLGKSPGSFQSNIITGKAGAQKTSEKHHAVSPAADQAFHTYGL
EWTPNYVRWTVDGQEVRKTEGGQVSNLTGTQGLRFNLWSSESAAWVGQFD
ESKLPLFQFINWVKVYKYTSDFTLDWTDNFDTFDGSRWGKGDYTFDGNRV
DLTDKNIYSRDGMLILALTRKGQESFNGQVPRDD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3axe Chain A Residue 3002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3axe Rational design to improve thermostability and specific activity of the truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase
Resolution1.53 Å
Binding residue
(original residue number in PDB)		N164 N189 G222
Binding residue
(residue number reindexed from 1)		N161 N179 G212
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) E56 E60
Catalytic site (residue number reindexed from 1) E53 E57
Enzyme Commision number 3.2.1.73: licheninase.
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3axe, PDBe:3axe, PDBj:3axe
PDBsum3axe
PubMed21959377
UniProtP17989|GUB_FIBSS Beta-glucanase (Gene Name=Fisuc_2961)

[Back to BioLiP]