Structure of PDB 2wf9 Chain A Binding Site BS04

Receptor Information

>2wf9 Chain A (length=221) Species: 1358 (Lactococcus lactis)

MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSRE
DSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLL
KDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDI
FIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVI
VPDTSHYTLEFLKEVWLQKQK

Ligand information

• Ligand ID: BEF
• InChI: InChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
• InChIKey: OGIAHMCCNXDTIE-UHFFFAOYSA-K
• SMILES:
  OpenEye OEToolkits 1.5.0: [Be-](F)(F)F
  ACDLabs 10.04
  CACTVS 3.341: F[Be-](F)F
• Formula: Be F3
• Name: BERYLLIUM TRIFLUORIDE ION
• PDB chain: 2wf9 Chain A Residue 1225

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2wf9 Near Attack Conformers Dominate Beta-Phosphoglucomutase Complexes Where Geometry and Charge Distribution Reflect Those of Substrate.
• Resolution: 1.4 Å
• Binding residue (original residue number in PDB): D8 L9 D10 S114 A115 K145
• Binding residue (residue number reindexed from 1): D8 L9 D10 S114 A115 K145
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): D8 L9 D10 T16 K45 S114 A115 K145 E169 D170
• Catalytic site (residue number reindexed from 1): D8 L9 D10 T16 K45 S114 A115 K145 E169 D170
• Enzyme Commision number: 5.4.2.6: beta-phosphoglucomutase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0008801 beta-phosphoglucomutase activity
• GO:0016853 isomerase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:2wf9, PDBe:2wf9, PDBj:2wf9
• PDBsum: 2wf9
• PubMed: 22505741
• UniProt: P71447|PGMB_LACLA Beta-phosphoglucomutase (Gene Name=pgmB)