Structure of PDB 2vj3 Chain A Binding Site BS04

Receptor Information
>2vj3 Chain A (length=120) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNP
CQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN
EFQCECPTGFTGHLCQVDLH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2vj3 Chain A Residue 1534 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2vj3 A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E511 H523
Binding residue
(residue number reindexed from 1)		E101 H113
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:2vj3, PDBe:2vj3, PDBj:2vj3
PDBsum2vj3
PubMed18660822
UniProtP46531|NOTC1_HUMAN Neurogenic locus notch homolog protein 1 (Gene Name=NOTCH1)

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