Structure of PDB 2p5g Chain A Binding Site BS04

Receptor Information
>2p5g Chain A (length=890) Species: 12353 (Escherichia phage RB69) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYF
DIYGKPCTRKLFANMRDASQWIKRMEDIGLEALGMDDFKLAYLSDTYNYE
IKYDHTKIRVANFDIEVTSPDGFPEPSQAKHPIDAITHYDSIDDRFYVFD
LLNSPYGNVEEWSIEIAAKLQEQGGDEVPSEIIDKIIYMPFDNEKELLME
YLNFWQQKTPVILTGWNVESFAIPYVYNRIKNIFGESTAKRLSPHRKTRV
KVIENMYGSREIITLFGISVLDYIDLYKKFSFTNQPSYSLDYISEFELNV
GKLKYDGPISKLRESNHQRYISYNIIAVYRVLQIDAKRQFINLSLDMGYY
AKIQIQSVFSPIKTWDAIIFNSLKEQNKVIPQGRSHPVQPYPGAFVKEPI
PNRYKYVMSFDLTSLYPSIIRQVNISPETIAGTFKVAPLHDYINAVAERP
SDVYSCSPNGMMYYKDRDGVVPTEITKVFNQRKEHKGYMLAAQRNGEIIK
EALHYRFDFSDEIKEKIKKLSAKSLNEMLFRAQRTEVAGMTAQINRKLLI
NSLYGALGNVWFRYYDLRNATAITTFGQMALQWIERKVNEYLNEVCGTEG
EAFVLYGDTDSIYVSADKIIDKVGESKFRDTNHWVDFLDKFARERMEPAI
DRGFREMCEYMNNKQHLMFMDREAIAGPPLGSKGIGGFWTGKKRYALNVW
DMEGTRYAEPKLKIMGLETQKSSTPKAVQKALKECIRRMLQEGEESLQEY
FKEFEKEFRQLNYISIASVSSANNIAKYDVGGFPGPKCPFHIRGILTYNR
AIKGNIDAPQVVEGEKVYVLPLREGNPFGDKCIAWPSGTEITDLIKDDVL
HWMDYTVLLEKTFIKPLEGFTSAAKLDYEKKASLFDMFDF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2p5g Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		K2 Y99
Binding residue
(residue number reindexed from 1)		K2 Y99
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2p5g, PDBe:2p5g, PDBj:2p5g
PDBsum2p5g
PubMed17718515
UniProtQ38087|DPOL_BPR69 DNA-directed DNA polymerase (Gene Name=43)

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