Structure of PDB 2gli Chain A Binding Site BS04
Receptor Information
>2gli Chain A (length=155) Species:
9606
(Homo sapiens) [
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ETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFK
AQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMC
EHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHV
KTVHG
Ligand information
Ligand ID
CO
InChI
InChI=1S/Co/q+2
InChIKey
XLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Co+2]
CACTVS 3.341
[Co++]
Formula
Co
Name
COBALT (II) ION
ChEMBL
DrugBank
DB14205
ZINC
PDB chain
2gli Chain A Residue 259 [
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Receptor-Ligand Complex Structure
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PDB
2gli
Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
C139 C144 H160 H164
Binding residue
(residue number reindexed from 1)
C37 C42 H58 H62
Annotation score
3
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000977
RNA polymerase II transcription regulatory region sequence-specific DNA binding
Biological Process
GO:0006357
regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634
nucleus
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Molecular Function
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Cellular Component
External links
PDB
RCSB:2gli
,
PDBe:2gli
,
PDBj:2gli
PDBsum
2gli
PubMed
8378770
UniProt
P08151
|GLI1_HUMAN Zinc finger protein GLI1 (Gene Name=GLI1)
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