Structure of PDB 2flc Chain A Binding Site BS04

Receptor Information
>2flc Chain A (length=247) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNLVELGSKTAKDGFKNEKDIADRFENWKENSEAQDWLVTMGHNLDEIKS
VKAVVLSGYKSDINVQVLVFYKDALDIHNIQVKLVSNKRGFNQIDKHWLA
HYQEMWKFDDNLLRILRHFTGELPPYHSNTKDKRRMFMTEFSQEEQNIVL
NWLEKNRVLVLTDILRGRGDFAAEWVLVAQKVSNNARWILRNINEVLQHY
GSGDISLSPRGSINFGRVTIQRKGGDNGRETANMLQFKIDPTELFDI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2flc Chain A Residue 248 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2flc DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		D62 Q81 V82
Binding residue
(residue number reindexed from 1)		D62 Q81 V82
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2flc, PDBe:2flc, PDBj:2flc
PDBsum2flc
PubMed16473850
UniProtQ5I6E6

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