Structure of PDB 2fct Chain A Binding Site BS04

Receptor Information
>2fct Chain A (length=304) Species: 321 (Pseudomonas syringae pv. syringae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKFALTAEQRASFEKNGFIGPFDAYSPEEMKETWKRTRLRLLDRSAAAYQ
DLDATNIANYDRHLDDDFLASHICRPEICDRVESILGPNVLCWRTEFFPK
YPGDEGTDWHQADTFANASGKPQIIWPENEEFGGTITVWTAFTDANIANG
CLQFIPGTQNSMNYDETKRMTYEPDANNSVVKDGVRRGFFGYDYRQLQID
ENWKPDEASAVPMQMKAGQFIIFWSTLMHASYPHSGESQEMRMGFASRYV
PSFVHVYPDSDHIEEYGGRISLEKYGAVQVIGDETPEYNRLVTHTTRGKK
FEAV
Ligand information
Ligand IDAKG
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(=O)CCC(=O)O
OpenEye OEToolkits 1.7.6C(CC(=O)O)C(=O)C(=O)O
CACTVS 3.385OC(=O)CCC(=O)C(O)=O
FormulaC5 H6 O5
Name2-OXOGLUTARIC ACID
ChEMBLCHEMBL1686
DrugBankDB08845
ZINCZINC000001532519
PDB chain2fct Chain A Residue 897 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2fct Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		F104 T113 H116 W145 L158 H235 R248 R254
Binding residue
(residue number reindexed from 1)		F98 T107 H110 W139 L152 H229 R242 R248
Annotation score5
Enzymatic activity
Enzyme Commision number 1.14.20.15: L-threonyl-[L-threonyl-carrier protein] 4-chlorinase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2fct, PDBe:2fct, PDBj:2fct
PDBsum2fct
PubMed16541079
UniProtQ9RBY6|SYRB2_PSESY L-threonyl-[L-threonyl-carrier protein] 4-chlorinase (Gene Name=syrB2)

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