Structure of PDB 2ero Chain A Binding Site BS04

Receptor Information
>2ero Chain A (length=426) Species: 8730 (Crotalus atrox) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNLTPEQQRYLNAKKYVKLFLVADYIMYLKYGRNLTAVRTRMYDIVNVIT
PIYHRMNIHVALVGLEIWSNTDKIIVQSSADVTLDLFAKWRATDLLSRKS
HDNAQLLTGINFNGPTAGLGYLGGICNTMYSAGIVQDHSKIHHLVAIAMA
HEMGHNLGMDHDKDTCTCGTRPCVMAGALSCEASFLFSDCSQKDHREFLI
KNMPQCILKKPLKTDVVSPAVCGNYFVEVGEECDCGSPRTCRDPCCDATT
CKLRQGAQCAEGLCCDQCRFKGAGTECRAAKDECDMADVCTGRSAECTDR
FQRNGQPCKNNNGYCYNGKCPIMADQCIALFGPGATVSQDACFQFNREGN
HYGYCRKEQNTKIACEPQDVKCGRLYCFPNSPENKNPCNIYYSPNDEDKG
MVLPGTKCADRKACSNGQCVDVTTPY
Ligand information
Ligand ID3CO
InChIInChI=1S/Co/q+3
InChIKeyJAWGVVJVYSANRY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Co+3]
FormulaCo
NameCOBALT (III) ION
ChEMBL
DrugBank
ZINC
PDB chain2ero Chain A Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2ero Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H238 H243
Binding residue
(residue number reindexed from 1)		H54 H59
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.-
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2ero, PDBe:2ero, PDBj:2ero
PDBsum2ero
PubMed16688218
UniProtQ9DGB9|VM3V1_CROAT Zinc metalloproteinase-disintegrin-like VAP1

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