Structure of PDB 2aoq Chain A Binding Site BS04

Receptor Information
>2aoq Chain A (length=220) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIPQTLEQLLSQAQSIAGLTFGELADELHIPVPIDLKRDKGWVGMLLERA
LGATAGSKAEQDFSHLGVELKTLPINAEGYPLETTFVSLAPLVQNSGVKW
ENSHVRHKLSCVLWMPIEGSRHIPLRERHIGAPIFWKPTAEQERQLKQDW
EELMDLIVLGKLDQITARIGEVMQLRPKGANSRAVTKGIGKNGEIIDTLP
LGFYLRKEFTAQILNAFLET
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2aoq Chain A Residue 233 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2aoq MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D70 E77 L78
Binding residue
(residue number reindexed from 1)		D62 E69 L70
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0006304 DNA modification
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2aoq, PDBe:2aoq, PDBj:2aoq
PDBsum2aoq
PubMed16209953
UniProtP44688|MUTH_HAEIN DNA mismatch repair protein MutH (Gene Name=mutH)

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