Structure of PDB 1w7c Chain A Binding Site BS04

Receptor Information
>1w7c Chain A (length=737) Species: 4922 (Komagataella pastoris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AECVSNENVEIEAPKTNIWTSLAKEEVQEVLDLLHSTYNITEVTKADFFS
NYVLWIETLKPNKTEALTYLDEDGDLPPRNARTVVYFGEGEEGYFEELKV
GPLPVSDETTIEPLSFYNTNGKSKLPFEVGHLDRIKSAAKSSFLNKNLNT
TIMRDVLEGLIGVPYEDMGCHSAAPQLHDPATGATVDYGTCNINTENDAE
NLVPTGFFFKFDMTGRDVSQWKMLEYIYNNKVYTSAEELYEAMQKDDFVT
LPKIDVDNLDWTVIQRNDSAPVRHLDDRKSPRLVEPEGRRWAYDGDEEYF
SWMDWGFYTSWSRDTGISFYDITFKGERIVYELSLQELIAEYGSDDPFNQ
HTFYSDISYGVGNRFSLVPGYDCPSTAGYFTTDTFEYDEFYNRTLSYCVF
ENQEDYSLLRHTGASYSAITQNPTLNVRFISTIGNYDYNFLYKFFLDGTL
EVSVRAAGYIQAGYWNPETSAPYGLKIHDVLSGSFHDHVLNYKVDLDVGG
TKNRASQYVMKDVDVEYPWAPGTVYNTKQIAREVFENEDFNGINWPENGQ
GILLIESAEETNSFGNPRAYNIMPGGGGVHRIVKNSRSGPETQNWARSNL
FLTKHKDTELRSSTALNTNALYDPPVNFNAFLDDESLDGEDIVAWVNLGL
HHLPNSNDLPNTIFSTAHASFMLTPFNYFDSENSRDTTQQVFYTYDDETE
ESNWEFYGNDWSSCGVEVAEPNFEDYTYGRGTRINKK
Ligand information
Ligand IDIMD
InChIInChI=1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)/p+1
InChIKeyRAXXELZNTBOGNW-UHFFFAOYSA-O
SMILES
SoftwareSMILES
CACTVS 3.341[nH]1cc[nH+]c1
ACDLabs 10.04c1c[nH+]cn1
OpenEye OEToolkits 1.5.0c1c[nH+]c[nH]1
FormulaC3 H5 N2
NameIMIDAZOLE
ChEMBL
DrugBank
ZINC
PDB chain1w7c Chain A Residue 821 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1w7c The 1.23 A Structure of Pichia Pastoris Lysyl Oxidase Reveals a Lysine-Lysine Cross-Link
Resolution1.23 Å
Binding residue
(original residue number in PDB)		Y396 I475 N477
Binding residue
(residue number reindexed from 1)		Y354 I433 N435
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Y384 D398 Y478 H528 H530 H694
Catalytic site (residue number reindexed from 1) Y342 D356 Y436 H486 H488 H652
Enzyme Commision number 1.4.3.-
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0008131 primary methylamine oxidase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0052597 diamine oxidase activity
Biological Process
GO:0009308 amine metabolic process
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1w7c, PDBe:1w7c, PDBj:1w7c
PDBsum1w7c
PubMed16929109
UniProtQ96X16

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