Structure of PDB 1om7 Chain A Binding Site BS04

Receptor Information
>1om7 Chain A (length=453) Species: 76981 (Pseudomonas sp. 'TAC II 18') [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTSSAFTQIDNFSHFYDRGDHLVNGKPSFTVDQVADQLTRSGASWHDNDG
VINLTYTFLTAPPVGYASRGLGTFSQFSALQKEQAKLSLESWADVAKVTF
TEGPAARGDDGHMTFANFSASNGGAAFAYLPNSSRKGESWYLINKDYQVN
KTPGEGNYGRQTLTHEIGHTLGLSHPGDNPTYRDAVYAEDTRAYSVMSYW
SEKNTGQVFTKTGEGAYASAPLLDDIAAVQKLYGANLETRADDTVYGFNS
TADRDFYSATSSTDKLIFSVWDGGGNDTLDFSGFSQNQKINLTAGSFSDV
GGMTGNVSIAQGVTIENAIGGSGNDLLIGNDAANVLKGGAGNDIIYGGGG
ADVLWGGTGSDTFVFGAVSDSTPKAADIIKDFQSGFDKIDLTAITKLGGL
NFVDAFTGHAGDAIVSYHQASNAGSLQVDFSGQGVADFLVTTVGQVATYD
IVA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1om7 Chain A Residue 705 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1om7 Probing the role of divalent metal ions in a bacterial psychrophilic metalloprotease: binding studies of an enzyme in the crystalline state by x-ray crystallography.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		N340 A342 N344 G357 G358 G359 D362
Binding residue
(residue number reindexed from 1)		N330 A332 N334 G347 G348 G349 D352
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.40: serralysin.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0005509 calcium ion binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0031012 extracellular matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1om7, PDBe:1om7, PDBj:1om7
PDBsum1om7
PubMed12837794
UniProtO69771

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