Structure of PDB 1lo1 Chain A Binding Site BS04

Receptor Information
>1lo1 Chain A (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECE
ITKRRRKSCQACRFMKALKVGMLKEGVRLDRVRGGRQKYK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1lo1 Chain A Residue 196 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1lo1 Monomeric Complex of Human Orphan Estrogen Related Receptor-2 with DNA: A Pseudo-dimer Interface Mediates Extended Half-site Recognition
ResolutionN/A
Binding residue
(original residue number in PDB)		C139 C145 C155
Binding residue
(residue number reindexed from 1)		C43 C49 C59
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1lo1, PDBe:1lo1, PDBj:1lo1
PDBsum1lo1
PubMed12654265
UniProtO95718|ERR2_HUMAN Steroid hormone receptor ERR2 (Gene Name=ESRRB)

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