Structure of PDB 1lat Chain A Binding Site BS04

Receptor Information
>1lat Chain A (length=71) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPCLVCSDEASGCHYGVLTCEGCKAFFKRAVEGQHNYLCKYEGKCIIDKI
RRKNCPACRYRKCLQAGMNLE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1lat Chain A Residue 1515 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1lat The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		C476 C482 C492 C495
Binding residue
(residue number reindexed from 1)		C39 C45 C55 C58
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1lat, PDBe:1lat, PDBj:1lat
PDBsum1lat
PubMed7664096
UniProtP06536|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)

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