Structure of PDB 1cz0 Chain A Binding Site BS04

Receptor Information
>1cz0 Chain A (length=162) Species: 5791 (Physarum polycephalum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALTNAQILAVIDSWEETVGQFPVITHHVPLGGGLQGTLHCYEIPLAAPYG
VGFAKNGPTRWQYKRTINQVVHRWGSHTVPFLLEPDNINGKTCTASHLCH
NTRCHNPLHLCWESLDDNKGRNWCPGPNGGCVHAVVCLRQGPLYGPGATV
AGPQQRGSHFVV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1cz0 Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1cz0 A novel endonuclease mechanism directly visualized for I-PpoI.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		C41 C100 C105 H110
Binding residue
(residue number reindexed from 1)		C40 C99 C104 H109
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) R61 H98 C105 N119
Catalytic site (residue number reindexed from 1) R60 H97 C104 N118
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing

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Molecular Function
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Biological Process
External links
PDB RCSB:1cz0, PDBe:1cz0, PDBj:1cz0
PDBsum1cz0
PubMed10581547
UniProtQ94702|PPO1_PHYPO Intron-encoded endonuclease I-PpoI

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