Structure of PDB 8ugj Chain 8A Binding Site BS04

Receptor Information

>8ugj Chain 8A (length=514) Species: 9823 (Sus scrofa)

MFVNRWLYSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGD
DQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNM
SFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSL
HLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVLITAVLLLLSLP
VLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPG
FGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVD
TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTV
GGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLF
SGYTLNQAWAKIHFVIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTAW
NTISSMGSFISLTAVMLMIFIIWEAFASKREVSAVELTSTNLEWLHGCPP
PYHTFEEPTYINLK

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8ugj Chain 8A Residue 607

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8ugj High-resolution in situ structures of mammalian respiratory supercomplexes.
• Resolution: 2.3 Å
• Binding residue (original residue number in PDB): H368 D369
• Binding residue (residue number reindexed from 1): H368 D369
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0004129 cytochrome-c oxidase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006119 oxidative phosphorylation
• GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
• GO:0015990 electron transport coupled proton transport

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0045277 respiratory chain complex IV

External links

• PDB: RCSB:8ugj, PDBe:8ugj, PDBj:8ugj
• PDBsum: 8ugj
• PubMed: 38811722
• UniProt: O79876|COX1_PIG Cytochrome c oxidase subunit 1 (Gene Name=MT-CO1)