Structure of PDB 7qi4 Chain 8 Binding Site BS04

Receptor Information

>7qi4 Chain 8 (length=151) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SEPLRKKKDQEAKERLKRKIRKLEKATQELIPIEDFITPLKFLDKARERP
QVELTFEETERRALLLKKWSLYKQQERKMERDTIRAMLEAQQEALEELQL
ESPKLHAEAIKRDPNLFPFEKEGPHYTPPIPNYQPPEGRYNDITKVYTQV
E

Ligand information

>7qi4 Chain B (length=72) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cagaguguagcuuaacacaaagcacccaacuuacacuuaggagauuucaa
cuuaacuugaccgcucugacca

<<<<<<...<<<........>>>.<<.<<.......>>.>>.....<<<<
......>>>>..>>>>>>....

Receptor-Ligand Complex Structure

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PDB	7qi4 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Resolution	2.21 Å
Binding residue (original residue number in PDB)	S122 K125 Q126
Binding residue (residue number reindexed from 1)	S70 K73 Q74

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0005515	protein binding

	Biological Process
GO:0009653	anatomical structure morphogenesis
GO:0032543	mitochondrial translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005761	mitochondrial ribosome
GO:0005762	mitochondrial large ribosomal subunit
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:7qi4, PDBe:7qi4, PDBj:7qi4
PDBsum	7qi4
PubMed	38769321
UniProt	Q9NQ50\|RM40_HUMAN Large ribosomal subunit protein mL40 (Gene Name=MRPL40)

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