Structure of PDB 7oj0 Chain 8 Binding Site BS04

Receptor Information
>7oj0 Chain 8 (length=353) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERA
QALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAEL
DALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYL
RWAESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVR
KSPFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSTESAVR
ITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMED
NKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQFIEASLK
AGL
Ligand information
>7oj0 Chain V (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cggcacguagcgcagcgguagcgcaccgucauggggugucgggggucgga
gguucaaauccucucgugccgacca
<<<<<<<..<<<<.......>>>>.<<<.<<.....>>.>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB7oj0 Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		E172 R278 K282
Binding residue
(residue number reindexed from 1)		E169 R266 K270
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006412 translation
GO:0006415 translational termination
GO:0075523 viral translational frameshifting
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7oj0, PDBe:7oj0, PDBj:7oj0
PDBsum7oj0
PubMed34403461
UniProtP07012|RF2_ECOLI Peptide chain release factor RF2 (Gene Name=prfB)

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