Structure of PDB 8ev7 Chain 2g Binding Site BS04

Receptor Information

>8ev7 Chain 2g (length=155) Species: 300852 (Thermus thermophilus HB8)

ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLAL
RWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAY
AHYRW

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8ev7 Chain 2g Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8ev7 Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
• Resolution: 2.89 Å
• Binding residue (original residue number in PDB): R32 D33
• Binding residue (residue number reindexed from 1): R31 D32
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8ev7, PDBe:8ev7, PDBj:8ev7
• PDBsum: 8ev7
• PubMed: 37537169
• UniProt: P17291|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)