Structure of PDB 8vtv Chain 2Q Binding Site BS04
Receptor Information
>8vtv Chain 2Q (length=141) Species:
300852
(Thermus thermophilus HB8) [
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MLMPRRMKYRKQQRGRLKGATKGGDYVAFGDYGLVALEPAWITAQQIEAA
RVAMVRHFRRGGKIFIRIFPDKPYTKKPLEVRMGKGKGNVEGYVAVVKPG
RVMFEVAGVTEEQAMEALRIAGHKLPIKTKIVRRDAYDEAQ
Ligand information
>8vtv Chain 2x (length=77) [
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cgcgggguggagcagccugguagcucgucgggcucauaacccgaaggucg
ucgguucaaauccggcccccgcaacca
.<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB
8vtv
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Resolution
2.55 Å
Binding residue
(original residue number in PDB)
P78 N89
Binding residue
(residue number reindexed from 1)
P78 N89
External links
PDB
RCSB:8vtv
,
PDBe:8vtv
,
PDBj:8vtv
PDBsum
8vtv
PubMed
39039256
UniProt
P60489
|RL16_THET8 Large ribosomal subunit protein uL16 (Gene Name=rplP)
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