Structure of PDB 8ud8 Chain 1m Binding Site BS04

Receptor Information

>8ud8 Chain 1m (length=123) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ARIAGVEIPRNKRVDVALTYIYGIGKARAKEALEKTGINPATRVKDLTEA
EVVRLREYVENTWKLEGELRAEVAANIKRLMDIGCYRGLRHRRGLPVRGQ
RTRTNARTRKGPRKTVAGKKKAP

Ligand information

InChI=1S/Mg/q+2

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Mg

Name

MAGNESIUM ION

PDB chain

8ud8 Chain 1m Residue 3001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	8ud8 An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance
Resolution	2.6 Å
Binding residue (original residue number in PDB)	T20 I22 I25
Binding residue (residue number reindexed from 1)	T19 I21 I24
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:8ud8, PDBe:8ud8, PDBj:8ud8
PDBsum	8ud8
PubMed	38359125
UniProt	P80377\|RS13_THET8 Small ribosomal subunit protein uS13 (Gene Name=rpsM)

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