Structure of PDB 7msm Chain x Binding Site BS03

Receptor Information
>7msm Chain x (length=553) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRIM
AGLDKPNNGDAFLATGATVGILQQEPPLNEDKTVRGNVEEGMGDIKIKLD
RFNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRCP
PADEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQH
LASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAER
LAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEKT
RKLDFEEIQIPVGPRLGNVVVEVDHLDKGYDGRALIKDLSFSLPRNGIVG
VIGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRKT
VWEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNRL
NLALTLKQGGNLILLDEPTNDLDVETLGSLENALLNFPGCAVVISHDRWF
LDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDAAVTHRKL
TRG
Ligand information
>7msm Chain y (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgggguggagcagccugguagcucgucgggcucauaacccgaaggucg
ucgguucaaauccggcccccgcaacca
.<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB7msm Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
Resolution2.79 Å
Binding residue
(original residue number in PDB)		S275 K278 A279 R280 R302 D411 Y412 R423 A424
Binding residue
(residue number reindexed from 1)		S274 K277 A278 R279 R301 D410 Y411 R422 A423
Enzymatic activity
Enzyme Commision number 3.6.1.-
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006417 regulation of translation
GO:0045900 negative regulation of translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7msm, PDBe:7msm, PDBj:7msm
PDBsum7msm
PubMed35064151
UniProtP9WQK3|ETTA_MYCTU Energy-dependent translational throttle protein EttA (Gene Name=ettA)

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