Structure of PDB 6fti Chain x Binding Site BS03

Receptor Information
>6fti Chain x (length=426) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIM
SSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGD
TPKDRALFNGAQKLFGMIITIGQSIVYVMSGICLLITIQLFVAGLIVLLL
DELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIA
LFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDL
PIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFPVG
GLCHYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKD
VAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLG
AIGSGTGILLAVTIIYQYFEIFVKEQ
Ligand information
>6fti Chain 0 (length=24) Species: 9615 (Canis lupus familiaris) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB6fti Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		K29 F40
Binding residue
(residue number reindexed from 1)		K25 F36
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005048 signal sequence binding
GO:0005515 protein binding
GO:0008320 protein transmembrane transporter activity
GO:0043022 ribosome binding
Biological Process
GO:0006613 cotranslational protein targeting to membrane
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0015031 protein transport
GO:0031204 post-translational protein targeting to membrane, translocation
GO:0039019 pronephric nephron development
GO:0045047 protein targeting to ER
GO:0045048 protein insertion into ER membrane
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005784 Sec61 translocon complex
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fti, PDBe:6fti, PDBj:6fti
PDBsum6fti
PubMed29519914
UniProtP38377|S61A1_CANLF Protein transport protein Sec61 subunit alpha isoform 1 (Gene Name=SEC61A1)

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