Structure of PDB 6vmi Chain v Binding Site BS03

Receptor Information
>6vmi Chain v (length=712) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVM
DSMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLD
GAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMGSNPARALQQ
MRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGQIVRYGEIP
AELRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLK
RSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKT
KILMNSSRDNSHPFVGLAFKLEVGRFGQLTYVRSYQGELKKGDTIYNTRT
RKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGL
SMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENK
ETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTH
KKQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKG
FLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALA
NATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVEDYFTLYA
DVPLNDMFGYSTELRSCTEGKGEYTMEYSRYQPCLPSTQEDVINKYLEAT
GQLPVKKGKAKN
Ligand information
>6vmi Chain A6 (length=71) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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<<.......<<<<.....>>>>.<<<<<.......>>>>>....<..<<.
.....>>..>....>.>....
Receptor-Ligand Complex Structure
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PDB6vmi Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Resolution2.96 Å
Binding residue
(original residue number in PDB)		K540 Q542 G545 Y549 M618 V619
Binding residue
(residue number reindexed from 1)		K501 Q503 G506 Y510 M579 V580
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0070125 mitochondrial translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6vmi, PDBe:6vmi, PDBj:6vmi
PDBsum6vmi
PubMed32737313
UniProtQ96RP9|EFGM_HUMAN Elongation factor G, mitochondrial (Gene Name=GFM1)

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