Structure of PDB 6rzz Chain u Binding Site BS03

Receptor Information
>6rzz Chain u (length=211) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AERVMQEKLRNRVDIPLEQCLFCEHNKHFKDVEENLEHMFRTHGFYIPEQ
KYLVDKIGLVKYMSEKIGLGNICIVCNYQGRTLTAVRQHMLAKRHCKIPY
ESEDERLEISEFYDFTSNDGIELHLPTGIKVGHRSLQRYYKQDLKPEVIL
TEGQGTLVAAETRSFLPAFDKKGVQTQQRVWQTERFDKKRLDKRSAKFVN
NQPHYRDQLLQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6rzz Chain u Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6rzz Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
C167 H187
Binding residue
(residue number reindexed from 1)
C23 H43
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006913 nucleocytoplasmic transport
GO:0007117 budding cell bud growth
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6rzz, PDBe:6rzz, PDBj:6rzz
PDBsum6rzz
PubMed31115337
UniProtP38344|REI1_YEAST Cytoplasmic 60S subunit biogenesis factor REI1 (Gene Name=REI1)

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