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Receptor Information

>5t5h Chain u (length=193) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VVKNKAYFKRFQVKYRRRREGKTDYQARRQMVLQDKTKFGTPKYRLVVRI
TNRDIIAQVVQAKVVGDEVVMAAYSHELPQFGIQHGLTNYAAAYATGLLV
ARRMLTKLFPFKAILDVGLARTTTGARVFGVMKGAVDGGLAVPHRPNRFP
GYDKEKDSLNAKAHRDRILGLHVAEYLELEGMYKKAHAAIRAD

>5t5h Chain D (length=114) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ggguacgaccauacuuggccggugcaccacaucccguccgauuugugaag
uuaagcggccacaggccucguuaguacggcgaucaguggcgcuggaaccc
ggggugcugcaauc

<<.<.<<......<<<<<<<<....<<<<<..............>>>..>
>....>>>>>>.>><<<<<<......<<<<<..<<.>>.>>>>>.....>
>>>>>..>>.>.>>

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5t5h Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Resolution	2.54 Å
Binding residue (original residue number in PDB)	K8 K10 F13 K14 F16 V18 Y20 R21 R22 R24 K27 T28 Y30 R33 V52 R54 T56 N57 R58 I61 Q63 V69 V70 G71 D72 E73 V74 Y79 N94 Y95 R158 T160 T161 A163 R164 P187 R204 H209 V210 Y213
Binding residue (residue number reindexed from 1)	K3 K5 F8 K9 F11 V13 Y15 R16 R17 R19 K22 T23 Y25 R28 V47 R49 T51 N52 R53 I56 Q58 V64 V65 G66 D67 E68 V69 Y74 N89 Y90 R121 T123 T124 A126 R127 P150 R167 H172 V173 Y176

Enzyme Commision number

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

PDB	RCSB:5t5h, PDBe:5t5h, PDBj:5t5h
PDBsum	5t5h
PubMed	27791004
UniProt	Q4CU61

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Structure of PDB 5t5h Chain u Binding Site BS03