Structure of PDB 7r6q Chain t Binding Site BS03

Receptor Information
>7r6q Chain t (length=290) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNSNPEILLRKRRNADRTRIERQELAKKKREEQIKKKRSNKNKFVRAESI
VAKTLATSREKERIKRVSILEDKKAKNETQHIASGKDFILKITEGLIREK
TTYDGKPALLFIVRVRGPLAVNIPNKAFKILSLLRLVETNTGVFVKLTKN
VYPLLKVIAPYVVIGKPSLSSIRSLIQKRGRIIYKGENEAEPHEIVLNDN
NIVEEQLGDHGIICVEDIIHEIATMGESFSVCNFFLQPFKLNREVSGFGS
LNRLRKIKQREAESRTRQFSNAATAPVIEVDIDSLLAKLN
Ligand information
>7r6q Chain 2 (length=57) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaacgcacauugcgccccuugguauuccagggggcaugccuguuugagc
gucauuu
.....<<<...>>><<<<<<<<<....>>>>>>>>>..............
.......
Receptor-Ligand Complex Structure
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PDB7r6q Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution2.98 Å
Binding residue
(original residue number in PDB)
K54 F55 R57 A152
Binding residue
(residue number reindexed from 1)
K43 F44 R46 A120
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000465 exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7r6q, PDBe:7r6q, PDBj:7r6q
PDBsum7r6q
PubMed36482249
UniProtP40693|RLP7_YEAST Ribosome biogenesis protein RLP7 (Gene Name=RLP7)

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