Structure of PDB 7o9k Chain t Binding Site BS03

Receptor Information
>7o9k Chain t (length=381) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHVNVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEERAR
GITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAAN
DGPMPQTREHLLLARQIGVEHVVVYVNKADEMVELVELEIRELLTEFGYK
GEETPVIVGSALCALEGRDPELGLKSVQKLLDAVDTYIPVPARDLEKPFL
LPVEAVYSVPGRGTVVTGTLERGILKKGDECELLGHSKNIRTVVTGIEMF
HKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSIKPHQKVEAQVYIL
SKEEGGRHKPFVSHFMPVMFSLTWDMACRIILPPEKELAMPGEDLKFNLI
LRQPMILEKGQRFTLRDGNRTIGTGLVTNTL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7o9k Chain t Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7o9k Structural basis for late maturation steps of the human mitoribosomal large subunit.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K70 T71 D126
Binding residue
(residue number reindexed from 1)		K16 T17 D72
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
GO:0045471 response to ethanol
GO:0070125 mitochondrial translational elongation
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0016020 membrane
GO:0042645 mitochondrial nucleoid
GO:0045202 synapse
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7o9k, PDBe:7o9k, PDBj:7o9k
PDBsum7o9k
PubMed34135318
UniProtP49411|EFTU_HUMAN Elongation factor Tu, mitochondrial (Gene Name=TUFM)

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