Structure of PDB 6hhq Chain sM Binding Site BS03

Receptor Information
>6hhq Chain sM (length=63) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEIVKSNTSSKKADVPPPSADPSKARKNRPRPSGNEGAIRDKTAGRRNNR
SKDVTDSATTKKS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6hhq Chain sM Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6hhq Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		N29 S31
Binding residue
(residue number reindexed from 1)		N7 S9
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030371 translation repressor activity
GO:0042162 telomeric DNA binding
GO:0043022 ribosome binding
GO:0045142 triplex DNA binding
GO:0061770 translation elongation factor binding
Biological Process
GO:0000723 telomere maintenance
GO:0006414 translational elongation
GO:0006417 regulation of translation
GO:0031929 TOR signaling
GO:0043066 negative regulation of apoptotic process
GO:0043558 regulation of translational initiation in response to stress
GO:0141014 ribosome hibernation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0048471 perinuclear region of cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6hhq, PDBe:6hhq, PDBj:6hhq
PDBsum6hhq
PubMed30759226
UniProtP39015|STM1_YEAST Suppressor protein STM1 (Gene Name=STM1)

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