Structure of PDB 8bhf Chain s3 Binding Site BS03
Receptor Information
>8bhf Chain s3 (length=170) Species:
9986
(Oryctolagus cuniculus) [
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KENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTV
RSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGF
GIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRI
SKEEAMRWFQQKYDGIILPG
Ligand information
>8bhf Chain B2 (length=119) [
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gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcu
<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB
8bhf
Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
N10 M12 R13 Q46 T47 V49 T73 R75 P137 G138 I141 K144 K145 R146 C150 I151 G152 A153 K154 H155
Binding residue
(residue number reindexed from 1)
N3 M5 R6 Q39 T40 V42 T66 R68 P130 G131 I134 K137 K138 R139 C143 I144 G145 A146 K147 H148
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005634
nucleus
GO:0005730
nucleolus
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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External links
PDB
RCSB:8bhf
,
PDBe:8bhf
,
PDBj:8bhf
PDBsum
8bhf
PubMed
37653241
UniProt
G1TUB8
|RL11_RABIT Large ribosomal subunit protein uL5 (Gene Name=RPL11)
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