Structure of PDB 8gzu Chain s1 Binding Site BS03

Receptor Information
>8gzu Chain s1 (length=689) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NKQIEIFIDGKPAKVDDSYTIFQACYENGVIVPRFCYHERLSVAGNCRMC
LVEVENVPKPVAACASQVVPGMKIKTKSEKTRIHRGNVMEFLLANHPLDC
PICDQGGECDLQDISSVYGYGISRYNEYKRAVEDKNYGPLVATSMNRCIH
CTRCVRFATQIAGVEDLGKTGRGKAAEIGTYVEKTFNTELSGNVVDVCPV
GALTNAPYAFTSRPWELKSFYTSDVFDTLGSAIQVDTRGPEIMRVLPRIH
EEINEEWISDKTRHAFDGLKRQRINSPMKRSKDGNYEDIFWEEAIQTISK
KCLNTPSDQIGAIIGEFADIESITALKDFLNRLDVDNFEVRQHGNLKVSP
DFRANYLMNSKITGVEDADVLLLVGCNPRYEAPVLNARILKSTRKNLKVF
NIGTNQDLNYKNVHLGNSTKVLKEIADGTHPFAERLKKAKLPMIMVGASA
LEREDGAELYNTLKVISNKTGVISEEKSWNGFNILHKEMGRINALELGIN
PTSVNKNAKLVFILGADNNLRPEDIPADAFVVYFGTHGDEGAYYADIILP
TAAYTEKNATWVNTEGRVQQGRLVVMPPGDAREDWQIIRALSEEAGVPLP
YDSLEELRYRVAELAPHLLKYDYIEPTIFGKVALSAQQGVKTTLSPTPIT
DYIDNFYMTDAISRASVTMAKCSTAFNHEKFSNFKNLAK
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8gzu Chain s1 Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8gzu Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Resolution4.18 Å
Binding residue
(original residue number in PDB)		C65 Y66 A73 G74 N75 C76
Binding residue
(residue number reindexed from 1)		C36 Y37 A44 G45 N46 C47
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:0045333 cellular respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8gzu, PDBe:8gzu, PDBj:8gzu
PDBsum8gzu
PubMed37248254
UniProtQ23KA9

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