Structure of PDB 8ovj Chain o Binding Site BS03

Receptor Information
>8ovj Chain o (length=88) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKRTVKMGVMGRYGTRYGANPRKRAKKLEVSQHAKHFCSFCGKFAFRRKA
VGIWRCDGCSKTVAGGAYTLSTPNNSTVRSTVRRLREL
Ligand information
>8ovj Chain 2 (length=1105) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguacacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaaaaauugccaacucaga
acugcuuacggcggggaauccaacuguauaauuaaaacauagguuuguga
ugcauccaagugguguauaucgcaaacugauuucugcccagugcucugaa
ugucaacgugacgagauucaccgacgcgcggguaaacggcgggaguaacu
augacucucuuaagguagccaaaugccucgucuuccaauuagagacgcgc
augaauggauuaaugagauucccucugucccgaguuacuaucuagcgaaa
cgacagucaagggaacggacuugaagggcuaagcggggaaagaagacccu
guugaguuugacuccagucuggcucugugcggcgacauccguugcuucac
uuaucgaaugaagagaccaauggguugcguagucuucgggcuaugcaccg
ucuagguuguggguacccaaccgugcuguaaacugaaccaacgggaguuc
cggagucuuguuucgagacaucugccagauggggaguuuggcuggggcgg
cauaucuguuacacgacaacgcagguguccuaaggcgagcucagugggaa
cagaucucacguagaacacaagcguaaaagcuugcuugauuaacgauuuc
caguacgaaucgagacugcgaaagcaaggccagcgauccuuugcgaagaa
uaggaaauaugaacaaaucauaccagaggugucagaauaauuaccacagg
gauaacuggcuuguggcggccaagcguucauagcgacgucgcuuuuugau
ccuucgaugucggcucuuccuaaccuagcgccgcagaagacgcuaagggu
uggauuguucacccacugacagggaacgugagcuggguuuagaccgucgu
gagacagguugguuuuacccuacuuagcuggaaauugcgagaaaaagauu
auccgugcaaagcggacguggcgagcgguggguaguacaugguacgcuca
ucacc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<...>>>>>..>>>>>>
.>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<..
..<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<....
<<<....<<<<......>>>>....>>>.>>>>..>>>>><<<<<<....
...>>>>>>........<...........<<<<<.......>>>>>....
.>.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>......
......<<<<<........>>>>>..<<<<<<<..<<<.<<......<<<
<.<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<<....>>>>>>.>>>
...<<<<<.....<<<<....<<...<<<<<<<<<..>>>>>>>>>.>>.
....<<<............>>>...................<<<<...>>
>>..>>>>...>>>>>.......>>>>>>>..>>>>>...<<<.....>>
>..<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.
....>>>>>>.....<<......>>....>>>>>>>...<<...<<<<<.
......>>>>>..>>.<<<....>>>.>>.........<<<<<.......
.......<<<<.......>>>>.>>>>>..........>>>>..>>>>>>
.......<<.<.<.<<<<<<...<<.......>>...>>>>>>...>>.>
.>.......<<<<<.<<<<<<..<<<<<<<.<......>.>>>>..>>>.
<<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....>>..>>>.>>>>>>>.....................
..<<<<.....>>>>.<<<.>>>.<.<<<<<<<.<<<<...>>>>>>>>>
>>.>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ovj Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		V6 K7 M8 G15 T16 R17 G19 A20 N21 R23 R87
Binding residue
(residue number reindexed from 1)		V5 K6 M7 G14 T15 R16 G18 A19 N20 R22 R86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ovj, PDBe:8ovj, PDBj:8ovj
PDBsum8ovj
PubMed38722744
UniProtQ4QC01

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