Structure of PDB 4u50 Chain m1 Binding Site BS03

Receptor Information

>4u50 Chain m1 (length=169) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

Ligand information

Ligand ID

OHX

InChI

InChI=1S/6H2N.Os/h6*1H2;/q6*-1;+6

InChIKey

OWCQTVJQFLTQTE-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 12.01 CACTVS 3.370 OpenEye OEToolkits 1.7.0	N[Os](N)(N)(N)(N)N

Formula

H12 N6 Os

Name

osmium (III) hexammine;
osmium(6+) hexaazanide

ChEMBL

DrugBank

ZINC

PDB chain

4u50 Chain m1 Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4u50 ?
Resolution	3.2 Å
Binding residue (original residue number in PDB)	D168 D170
Binding residue (residue number reindexed from 1)	D163 D165
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4u50, PDBe:4u50, PDBj:4u50
PDBsum	4u50
PubMed	25209664
UniProt	Q3E757\|RL11B_YEAST Large ribosomal subunit protein uL5B (Gene Name=RPL11B)

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